Guide

Antidepressants and libido

A real, common, and under-discussed side effect — and a conversation worth having with a prescriber rather than solving by stopping.

Reviewed by Albert Wong, PhDClinical psychologistLast reviewed September 2026About this site

General information, not medical advice, and nothing here is a reason to stop a prescription on your own.

Sexual side effects from SSRIs and SNRIs are common — estimates vary widely and the higher-quality ones are substantial, considerably above what the original trial reporting suggested. They affect desire, arousal, and orgasm, and they’re one of the leading reasons people stop antidepressants without telling anyone.

What it looks like

Reduced desire. Delayed orgasm, or inability to reach it. Reduced genital sensation, sometimes described as numbness. Erectile difficulty. And a specific and disorienting one: intact desire with a body that does not respond, or orgasm without much sensation attached.

It typically appears within the first weeks and, unlike nausea and jitteriness, frequently doesn’t resolve with time.

The conversation to have

The most important point on this page: this is a modifiable problem and a great many people never mention it.

Prescribers frequently don’t ask, and patients frequently don’t raise it, so it goes unaddressed for years — and it’s one of the strongest predictors of people quietly stopping medication that was working.

Say it plainly: this medication has affected my sexual function, and I would like to talk about options.

What the options generally are

Decided with a prescriber, and the usual ones are:

Dose adjustment. Sometimes sufficient.

Switching. Some antidepressants have markedly lower rates of sexual side effects — bupropion and mirtazapine among them — and a switch is frequently the cleanest answer.

Augmentation. Adding something to counteract it, which is an established approach.

Timing changes, for some medications.

And waiting, where the depression is severe enough that treating it takes priority for now — which is a legitimate decision, made deliberately rather than by default.

The other medications

Not only antidepressants. Also implicated: some blood pressure medications, particularly beta blockers and thiazides. Finasteride. Some hormonal contraceptives, for some people. Antipsychotics. Opioids. And alcohol, in the longer term.

If desire or function changed after starting something, the timing is the most useful information you have.

The complication

Depression itself lowers desire, substantially. So a person on an antidepressant with low desire has two candidate explanations, and disentangling them requires a proper conversation rather than an assumption in either direction.

A useful discriminator: if desire dropped clearly after starting the medication, having been present before, that points at the medication. If it was absent during the depression and hasn’t returned, that may be incomplete treatment rather than a side effect.

What not to do

Stop suddenly. Discontinuation effects from several antidepressants are genuinely unpleasant, and relapse rates are high. Whatever you decide, do it with a prescriber and taper properly.

And don’t spend months in intimacy work on a problem that has a pharmacological cause — which is a meaningful risk here, and a competent practitioner will ask about your medication in the first session. More on that boundary.

Keep reading

46 guides on embodiment, desire and intimacy, free and without an account. There is a directory here too — it is new, and growing.

General information for adults, not clinical or medical advice; the people described are composites, not real clients. Nothing here is a substitute for care from a licensed clinician or physician, and pain, bleeding, or a sudden change in sexual function is a medical question first. No practitioner listed on this site offers touch, surrogate partner work, or sexual services. Listings are maintained by independent practices. If you are in immediate danger, call 911; the 988 Suicide & Crisis Lifeline is available any time, and the National Domestic Violence Hotline is 1-800-799-7233.